Consumption of analgesics before a marathon and the incidence of cardiovascular, gastrointestinal and renal problems

 The bottom link or take home messaged from this study is save your pain meds for after the marathon, not before.

 The link below is a study that looks at consumption of over the counter pain medications before a marathon and the incidence of complications. The authors concluded,"the use of analgesics before participating in endurance sports may cause many potentially serious, unwanted analgesic effects (AEs) that increase with increasing analgesic dose. Analgesic use before endurance sports appears to pose an unrecognised medical problem as yet. If verifiable in other endurance sports, it requires the attention of physicians and regulatory authorities."

http://www.ncbi.nlm.nih.gov/pubmed/23604350